ISHIZUKA Dojo
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Sensory information from the external world is transmitted from the cerebral cortex to the hippocampus, but not everything transmitted is memorized. Rather, information is selected, linked and fixed. One goal of our laboratory is to clarify how the hippocampus processes information, focusing on the flow of electric signals and neuronal connections. Slices of living hippocampus tissue are trimmed from rat brains and artificial electric signals with various pulse speeds and combinations are inputted through the neurons to determine which signal patterns are easily transmitted and how the hippocampus responds. The neurons are also stained in order to observe the intercellular connections.

Students experiment on living hippocampus preparations from rat brains, stimulating them electrically and measuring electric potential to develop the basic skills required for electrophysiological experiments. Engineering students usually study signals through textbooks and simulations, but in our program they apply stimuli directly to living tissue to experience how electric signals are expressed and successively transmitted. This increases the students' familiarity with electrical signals transmitted through the nerves. As good preparations can only be obtained through the proper care and management of experimental animals, students are also directly involved in all aspects of animal care so that the lives of these animals are not sacrificed wastefully.



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